T cells are white blood cells that are important for adaptive immunity. They have unique ... interaction has been a central dogma of T cell-mediated responses. Here the authors use X-ray ...

The immune system works to maintain homeostasis throughout the body. Various cell types and immune mechanisms work in concert ...

The first step in the interaction between MSCs and their target cells involves cell–cell contact mediated by adhesion molecules, as indicated by studies showing that the inhibition of T-cell ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

Basophils trigger a cytokine cascade that improves antitumor immunity in mice ... the researchers observed fewer T cells and a reduction in cytokine levels, including interleukin-3 (IL-3), hallmarks ...

Although there are tumor suppressor genes in normal cells to prevent cancer ... Finally, CD8 + T cell-mediated antitumor ...

Memory T cells ... cell responses develop following SARS-CoV-2 infection, and that COVID-19 vaccination enhances both the frequency and function of these cells, contributing to long-lasting immunity.

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

The ability to therapeutically manipulate the immune system presents a multitude of potential opportunities for treating infectious diseases, cancer and other diseases, but first, researchers must ...