FDA has cleared an investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy (CLBR001 + SWI019) in patients with autoimmune conditions. Patient ...

Even in the case of uncomplicated infections, the body prepares itself early on for the possibility of a more severe course. A research team has now uncovered this mechanism. The scientists showed ...

Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing ...

Ischemic heart disease is a common consequence of coronary artery disease (CAD), which is primarily driven by atherosclerosis, a chronic inflammatory ...

Calibr-Skaggs Institute for Innovative Medicines, the drug discovery division of Scripps Research, announced today that the FDA has cleared their investigational new drug (IND) application to study ...

Madeleine R. Heldman, MD, MS, discusses managing cytomegalovirus, including advances in CMV assessment and antiviral and immune strategies.

Clinical samples provided evidence for macrophage-mediated CD47-dependent phagocytosis of CAR-T cells, further supported by a patient-derived xenograft model of DMG relapse following a low-dose ...