Twelve months after revaccination, antibody levels declined but remained significantly higher than baseline in patients with CLL.

USC researchers have developed an innovative type of cancer-fighting immune cell, the EchoBack CAR T-cell, that uses focused ...

A stable interaction between antigen-presenting cells (APC) and T cells is dependent not only on the absolute affinity between the T-cell receptor (TCR) and its ligand but also on the relative ...

A new study has revealed that a special group of cells in the intestines tamp down the immune responses caused by exposure to food proteins. Called 'tolerogenic dendritic cells,' these cells enable ...

Tolerogenic dendritic cells in the intestines are shown to reduce the immune responses caused by exposure to food proteins.

The TCEs activate T cells in an antigen-dependent manner, bypassing the need for costimulatory signals. Once activated, T ...

Compromised antigen presentation ranks among the top mechanisms that render cancers non-immunogenic (non-responsive to immune ...

New research zeroes in on a unique group of immune cells that could transform how we treat—and possibly prevent—severe food ...

This creates a batch of T cells able to recognize and destroy that particular antigen. In research published ... Joshua Biggs O'May et al, WNK1-dependent water influx is required for CD4+ T ...

Typically, dendritic cells present tiny fragments of biological material (known as antigens) for notice by other immune cells called T cells. This programs the T cell to launch an immune attack the ...

Chimeric antigen receptor (CAR) T cell therapies have made ... Clinical samples provided evidence for macrophage-mediated CD47-dependent phagocytosis of CAR-T cells, further supported by a ...