The Rams host the banged-up 49ers on Sunday with a 7-game losing streak to San Francisco in the regular season on the line and Christian McCaffrey in backfield.

End of third quarter: 49ers 6, Rams 3. The only scores have been a few field goals so far through 45 minutes. However, the Rams will begin the fourth quarter on San Francisco's 4-yard line.

Not a single touchdown was scored, but the Los Angeles Rams picked up a crucial NFC West victory over the San Francisco 49ers on Thursday night, 12-6. The Rams moved to 8-6, while the 49ers fell ...

Nov. 15, 2021: 49ers 31, Rams 10 at Levi’s Stadium. The 49ers were on the brink of an early exit in the playoff race with a 3-5 record. The Rams were 7-2 and on their way to an NFC West title.

The Rams defense is playing exceptionally well, keeping the 49ers at just 108 total yards in the first 30 minutes. The 49er run game has been silent with just 20 total yards on the ground.

The Los Angeles Rams and San Francisco 49ers square off in the Week 15 edition of "Thursday Night Football." Sports newsletter 🏈's best, via 📧 Studio IX 🏀⚽️🥇 Golfweek.com ...

Q2 0:41 Rams 3, 49ers 3On third-and-4, Brock Purdy heaves a deep ball to Jauan Jennings. Quentin Lake breaks the play up, resulting in an incomplete pass.It's a three-and-out for the 49ers offense.

Q2 5:40 Rams 0, 49ers 3 Brock Purdy had a lot of space to pick up the first down. But on third-and-11, Kobie Turner doesn't give up on the play, showcasing his motor to sack Purdy for the second ...

Last meeting: Rams beat 49ers 27-24 in Inglewood, Calif., on Sept. 22, 2024. Last week: Rams beat the Bills 44-42; 49ers beat the Bears 38-13.

The Los Angeles Rams visit the San Francisco 49ers for Week 15 of Thursday Night Football at 8:15 p.m., only on Prime Video. You can watch for free with Amazon Prime free trial.

The 49ers are 2.5-point favorites in the latest Rams vs. 49ers odds, while the over-under for total points scored is 48.5. The 49ers are -154 money-line favorites, while the Rams are +129 underdogs.