Over 130 voting cardinals must decide whether to continue in the direction of Francis or elect a pope likely to choose a more traditional path.

The first papal conclave in 12 years begins on Wednesday at the Vatican after a morning Mass in St. Peter’s Basilica. At 4:30 p.m. local time (10:30 a.m. Eastern), the cardinals will walk in a short procession to the Sistine Chapel from the nearby Pauline Chapel to begin the vote.