Fluorescent probes have transformed our ability to interrogate DNA and RNA at the levels of sequence, structure and dynamic behaviour. By integrating intrinsic labels—nucleobase analogues that retain ...
About nonradioactive nucleic acid detection -- Isolation of DNA from plants -- Isolation of high-molecular-weight DNA from animal cells -- Restriction enzyme digestion, gel electrophoresis and vacuum ...
Labelling of nucleic acid amplicons during polymerase chain reaction (PCR) or isothermal techniques is possible by using both labelled primers and labelled nucleotides. While the former is the widely ...
Improve assay sensitivity and specificity with Locked Nucleic Acid oligonucleotides (LNA oligos) from LGC Biosearch Technologies. LNAs are RNA bases in which the ribose is “locked” with a methylene ...
Article reviewed by Govind Kaigala, PhD at the University of British Columbia. Stay up to date on the latest science with Brush Up Summaries. In situ hybridization (ISH) is a molecular technique that ...