A high-resolution crystal structure of the ligand-binding domain of the human nicotinic acetylcholine receptor α subunit, with three point mutations to improve its crystallization, provides both ...

Here we present the crystal structure of molluscan acetylcholine-binding protein (AChBP), ... Unwin, N. Nicotinic acetylcholine receptor at 9 Å resolution. J. Mol.

Researchers 'See' Structure Of Open Nicotinic Acetylcholine Ion Channels. ScienceDaily . Retrieved June 4, 2025 from www.sciencedaily.com / releases / 2008 / 04 / 080407153039.htm ...

Researchers 'see' structure of open nicotinic acetylcholine ion channels Peer-Reviewed Publication. University of Illinois at Urbana-Champaign, News Bureau ...

The researchers say that their study reveals how the muscle nicotinic acetylcholine receptor-a neurotransmitter-gated ion channel that regulates the flow of information in the form of charged ...

To determine the correlation between SARS-CoV-2 and nicotinic acetylcholine receptors (nAChRs), the researchers studied a panel of co-crystal structures along with the neurotoxin binding motif ...

Preliminary scientific report. Oliveira, A.S.F. et al. (2020). Simulations support the interaction of the SARS-CoV-2 spike protein with nicotinic acetylcholine receptors and suggest subtype ...

Bionomics Announces Update on the α7 Nicotinic Acetylcholine Receptor (nAChR) Positive Allosteric Modulator (PAM) Collaboration with MSD. Bionomics Ltd . Thu, Sep 14, 2023, 6:00 AM 4 min read.

When nicotine enters the brain, it binds to nicotinic acetylcholine receptors (nAChRs) on the surface of neurons. Usually bound to by the neurotransmitter acetylcholine, activation of these excitatory ...