In contrast to neural crest-derived stem cells, which have a limited self-renewal capacity, pNSCs closely resemble brain-derived NSCs and show the ability to sustain neurogenesis over an extended ...

Human embryonic stem cells display neural crest characteristic expression after only five days of culture under WNT induction. Transcription factors SOX10 and PAX7 are seen in green and red ...

Intro text here... Abnormal neural crest cell development is associated with numerous pathologies including craniofacial malformations such as cleft lip and cleft palate, rare syndromes, and ...

The discovery of peripheral neural stem cells outside the central nervous system suggests a previously unrecognised level of cellular plasticity within the nervous system. In contrast to neural ...

The discovery of peripheral neural stem cells outside the central nervous system suggests a previously unrecognised level of cellular plasticity within the nervous system. In contrast to neural ...

Another key regulator is SOX10, which is required for the gereration of Schwann cell precursors from the neural crest. Understanding the signals that regulate the appearance of glial ...

In the cerebral cortex, different neuronal cell types are generated in a temporally defined sequence and constitute the cortical layers; neural stem cells then switch off neuron production to make ...

To address this question in detail, one must first have an accurate map of the diverse patterns of investment by SMC ...

Right panels: Lab-grown cortical interneurons from human pluripotent stem cells are tools to study psychiatric disorders. Specific functional, electric firing properties of those neurons are shown by ...