Nephrogenic systemic fibrosis is a progressive disease that affects the skin and vital organs. Nearly all cases of this ...

The fibrosis seems to be triggered by an unknown antigenic stimulus that causes the migration of bone-marrow-derived 'circulating fibrocytes' to the skin and other systemic locations and the ...

The subcutaneous tissue, however, showed broad bands of fibrosis intersecting in a haphazard ... as being consistent with a diagnosis of nephrogenic fibrosing dermopathy (NFD).