Nature

Regions of homozygosity identified by SNP microarray analysis aid in the diagnosis of autosomal recessive disease and incidentally detect parental blood relationships

The purpose of this study was to document the ability of single-nucleotide polymorphism microarray to identify copy-neutral regions of homozygosity, demonstrate clinical utility of regions of ...
Nature

Patterns of homozygosity in patients with uniparental disomy: detection rate and suggested reporting thresholds for SNP microarrays

Single-nucleotide polymorphism (SNP) microarrays can easily identify whole-chromosome isodisomy but are unable to detect whole-chromosome heterodisomy. However, most cases of uniparental disomy (UPD) ...
Fierce Healthcare

ARUP Laboratories Announces Its Newest SNP-Based Microarray Technology

SALT LAKE CITY--(BUSINESS WIRE)-- ARUP Laboratories, a leading national clinical and anatomic pathology reference laboratory and a leader in innovative laboratory research and development, is pleased ...
Medscape

Microarray-Based Prenatal Diagnosis for the Identification of Fetal Chromosome Abnormalities

The sequencing of the human genome afforded the development of chromosomal microarrays that can be used to detect gains and losses of the genome. Microarrays are constructed from large pieces of ...
The New England Journal of Medicine

Karyotype versus Microarray Testing for Genetic Abnormalities after Stillbirth

Genetic abnormalities have been associated with 6 to 13% of stillbirths, but the true prevalence may be higher. Unlike karyotype analysis, microarray analysis does not require live cells, and it ...
The New England Journal of Medicine

Chromosomal Microarray versus Karyotyping for Prenatal Diagnosis

Chromosomal microarray analysis has emerged as a primary diagnostic tool for the evaluation of developmental delay and structural malformations in children. We aimed to evaluate the accuracy, efficacy ...
Nanowerk

Microarray Definition: How DNA Microarrays Work, Types, and Uses

Definition: A microarray is a small, flat substrate carrying an ordered grid of microscopic probe features, each containing a known biological molecule, that is used to measure many molecular targets ...
GEN

Improving LOH Detection on CGH Microarrays

Due to its higher resolution, oligo array CGH has recently made strong inroads in the cytogenetic lab. It’s not surprising. With an increased sensitivity of more than 1,000-fold, microarrays can ...
News Medical

Microarray Applications

Reviewed by Dr. Tomislav Meštrović, MD, Ph.D. The microarray is a very recent development in the field of biotechnology. Scientists are now able to understand the gene functions of any organism by ...
GEN

Utilization of DNA Microarrays Increasing

Persistent Doubts about Reproducibility and Compatability of Data Are Being Overcome One of the hottest research tools these days within the academic, biotech, and pharma communities is DNA ...
technologynetworks

Agilent Appoints NIMGenetics as Spain’s First Certified Service Provider for CGH and CGH/SNP Microarrays

Agilent Technologies, Inc. has announced that NIMGenetics S.L. of Madrid has achieved Certified Service Provider (CSP) status for genomic research using Agilent SurePrint comparative genomic ...
Medscape

Microarray-Based Prenatal Diagnosis for the Identification of Fetal Chromosome Abnormalities

Expert Rev Mol Diagn. 2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that the ...