Scientists have uncovered a surprising new trick used by one of cancer’s most notorious proteins. MYC, already infamous for fueling runaway tumor growth, also appears to help cancer cells survive by ...

“The mice that we created are long-lived, but they are incredibly normal, and they are incredibly healthy,” said study coauthor John Sedivy, who studies aging and cancer at Brown University in ...

Novel Treatment Targets in Sarcoma: More Than Just the GIST MYC has proven to be a highly potent oncoprotein when it is overexpressed, but is also a pleiotropic transcription factor essential for ...

MYC proteins play an important role in many types of cancer. A research team at the University of Würzburg has now succeeded in indirectly influencing these proteins—with clear consequences for the ...

Northwestern Medicine investigators have discovered a new combination approach that may improve the efficacy of MYC inhibitor drugs for treating aggressive and treatment-resistant cancers, according ...

A new review in Genes and Diseases explores the central role of MYC, a master regulatory protein, in the development and progression of cancer, spotlighting its potential as a multidimensional ...

The MYC oncogene family plays an important role in neoplastic disease, and has been extensively studied over decades. Evidence showing the N-terminal and C-terminal regions of MYC can function as a ...