Other heavyweights like Lady Gaga, Doechii, Ariana Grande, and Taylor Swift are also nominated, while newcomers like Bella Kay and CORTIS are only some of the 26 first-time nominees at this year's show, which hits CBS on Sunday, September 27.

If Madonna wins, she'll establish a new record for the longest span of video of the year wins: 28 years.

Rock music had been a staple of the MTV Video Music Awards since it began in 1984, when The Cars won Video of the Year for “You Might Think.” Rock artists dominated the top VM