This led them to a dual-action antibiotic called VCD-077, which was loaded into a bone cement made from polymethylmethacrylate (PMMA), the FDA-approved gold-standard.

In fact, VCD-077-loaded PMMA bone cement exhibited greater efficacy than all currently used antibiotic-loaded bone cements against Staphylococcal bone infections in a rat model.

A potent antibiotic-loaded bone-cement implant against staphylococcal bone infections. Nature Biomedical Engineering , 2022; DOI: 10.1038/s41551-022-00950-x Cite This Page : ...

Published results showed antibiotic-loaded bone cement may not be warranted for prophylaxis with total knee arthroplasty due to the additional cost and similar rates of revision for periprosthetic ...

3D printing with bacteria-loaded ink produces bone-like composites. Ecole Polytechnique Fédérale de Lausanne. Journal Materials Today DOI 10.1016/j.mattod.2023.02.001. Keywords ...