The structure and receptor-binding characteristics are presented of the haemagglutinin (HA) from an avian H10N2 virus that closely resembles an isolate from recent human fatalities; although avian ...

A variant of the bird flu virus, collected in 2016 and no longer in circulation, was just one mutation away from being able to bind to human receptors. This finding underscores that certain bird ...

The shift in the receptor-binding specificity of influenza A viruses is mostly determined by mutations in viral haemagglutinin. In this Review, Gao and colleagues discuss recent crystallographic ...

Modest changes in the 1918 flu virus's hemagglutinin receptor binding site--a molecular structure critical for the spread of infection--stopped viral transmission in ferrets, according to a new ...

Avian influenza viruses are dotted with surface proteins that allow them to bind to bird cell receptors, which permit the virus to enter the cells.

Modest changes in the 1918 flu virus's hemagglutinin receptor binding site -- a molecular structure critical for the spread of infection -- stopped viral transmission in ferrets, according to a ...

A new study found that a single mutation to the hemagglutinin protein of an H5N1 virus isolated from a dairy worker in Texas this spring switched the protein’s binding specificity from avian- to ...

Recent study reveals H5N1 mutations enhancing human receptor binding, highlighting pandemic risks and the need for vigilant surveillance of influenza strains.

However, seasonal H1N1 influenza could only attach to α2-6. "Receptor binding determines how well a virus spreads between cells and causes an infection," said Professor Feizi.

Influenza viruses infect hosts by binding to sialic acid receptors in the respiratory tract. Avian viruses preferentially bind to α2,3-linked receptors, while human viruses target α2,6-linked ...

(Modest changes in the 1918 flu virus's hemagglutinin receptor binding site—a molecular structure critical for the spread of infection—stopped viral transmission in ferrets, according to a new ...