Genetic modification aimed at understanding the function and pathology associated with specific genes is most commonly undertaken in mice, as about 99 percent of human genes have mouse orthologs. 1 ...

Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19. According to their new study in ...

A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling. Scientists at The University of Texas Health Science Center at San Antonio have created ...

A new study published in Microbiology Spectrum reports the establishment of a liver-humanized NSG-PiZ mouse model that is fully permissive to hepatitis B virus (HBV) infection. In this model, HBV can ...

Michael Brehm will speak on Wednesday, April 12 at 3:30 p.m. in Coburn G30 and provide an overview of immunodeficient mouse strains for humanization, then focusing on Engraftment of human immune ...

Due to advancements in genetic engineering, small animal models are continuing to change in response to market needs. Model developers strive to better reflect the role of this important asset in both ...

Lunai Bioworks (NASDAQ: LNAI), an AI-powered drug discovery and biodefense company, today announced it has secured its first ...

Researchers generate cutting-edge mouse models by engrafting human cells and tissue into the animals to better study the human immune system. Scientists have employed mouse models in immunological ...

Humanized immune system (HIS) mouse models have become indispensable for advancing translational research in immuno-oncology, autoimmune disorders, and infectious disease. This webinar will begin with ...

For the first time, scientists have successfully created a type of mouse with a 100% functional human immune system and human-like gut microbiome. This 'humanized' mouse takes the guesswork out of ...