RNA bundled in lipid nanoparticles trains T cells in mice to eliminate cancer. Coupled with noninvasive imaging, researchers tracked the in situ CAR-T cells to assess their effectiveness and safety.

Dr. Olalekan O. Oluwole explained how CAR T is used to treat high-risk blood cancers and highlighted the potential of ...

Genetically modified T cells are therefore proving to be of great value for basic immunology and experimental immunotherapy.

Treating types of cancer with CAR T-cell therapy is expensive and inconvenient, but a streamlined approach that creates the therapy within the body could make the intervention cheaper and easier ...

The Food and Drug Administration has announced new guidelines that will make CAR T-cell therapy more accessible to cancer ...

Would you get a one-time genetic modification such that you'd never have to take a GLP-1 drug for weight loss ever again?

A prime example is chimeric antigen receptor (CAR) T-cell therapy, where T cells are harvested from the blood of a cancer patient and genetically engineered to recognize an antigen expressed on ...

Scientific organizations recently called for a 10-year ban on human germline editing. But will we ever be ready? And how would we even know?

CAR-T cells are specialized immune cells genetically modified to recognize and attack cancer cells. Researchers at Nagoya University in Japan and their collaborators have developed new CAR-T cells ...

CAR-T cells are genetically modified T cells that express a synthetic receptor designed to recognize a surface protein found on tumor cells. Tumor-infiltrating lymphocytes (TILs) are natural T ...

Dr Dinesh Pendharkar highlights how CAR T–cell therapy is reshaping cancer care in India by equipping the immune system with ...

T cells are a natural part of the immune system designed to fight infections and cancer, but in conditions like blood cancer, ...