Common fragile sites (CFSs) are specific chromosomal regions that become prone to breakage when cells experience impediments to DNA replication. These loci often coincide with large, late-replicating ...
Fragile X syndrome (FXS) is caused by the expansion of a CGG trinucleotide repeat in the 5′ untranslated region of the FMR1 gene, resulting in epigenetic silencing of FMR1 and consequent loss of ...
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