During the maternal-to-zygotic transition in Drosophila, the pioneer transcription factors Zelda and GAF jointly regulate the transcriptional activation of zygotic genes in the early embryo ...

Diffusion plays unusual signaling role in drosophila embryos, researchers find. ScienceDaily . Retrieved May 20, 2025 from www.sciencedaily.com / releases / 2017 / 11 / 171116132719.htm ...

Watching and measuring what happens in tissues inside the human embryo is currently not possible, and it's difficult to do in mammalian models. Because humans and the fruit fly Drosophila share so ...

Recent research from the Developmental and Regulatory Genomics group showed that the 3D genome structure of the Drosophila embryo was established at the onset of zygotic genome activation, an early ...

Results of the study were published in PNAS on Nov. 14 as "HIRA and dPCIF1 coordinately establish totipotent chromatin and control orderly ZGA in Drosophila embryos." The zygotic genome remains ...

Details of this work appeared August 31 in the journal Science, in an article entitled “The Drosophila Embryo at Single-Cell Transcriptome Resolution.” “We produce a virtual embryo with ...

The study harnesses data from over one million embryonic cells spanning all stages of embryo development and represents a significant advance at multiple levels. “Just capturing the entirety of ...

They all look alike under the microscope. However, each cell of a Drosophila melanogaster embryo already knows by then whether it is destined to become a neuron or a muscle cell—or part of the ...

By combining powerful Drosophila genetics with 3D genome modeling, they discovered that HP1a is required to establish a proper chromatin 3D structure at multiple hierarchical levels during early ...

This video from Carl Zeiss shows a 3D representation of reconstructed Multiview recordings of a Drosophila embryo expressing fluorescently tagged BAC clone (GFP). The gene is cystein string protein, ...