DNA hairpin substrates. The two DNA hairpin substrates were made from the same 1.1 kilobase pair insert of plasmid pNo_GTT (Supplementary Methods) sequentially digested with restriction enzymes ...

The length of the DNA hairpin stems was varied by adding or removing base pairs from a well-characterized 6-bp hairpin 10. Unless otherwise noted, the hairpin loops were composed of 4dT, ...

Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly. Journal of the American Chemical Society, 2022; DOI: 10.1021/jacs.2c08974; ...

Hairpin-Shaped, Cancer-Curing DNA. The research team produced a pair of hairpin-shaped, cancer-curing DNA molecules using chemical synthesis. The microRNA (miRNA) molecules that are overproduced ...

One is called a "catalytic DNA hairpin mediator," which is a single-stranded DNA molecule that partially pairs up with itself to form a hairpin structure with a short overhanging single strand.

CRISPR breakthrough uses "hairpin lock" for more precise genetic engineering By Michael Irving. April 16 ... CRISPR is a type of DNA sequence that bacteria use to defend themselves from viruses.

DNA origami exploits the base pairing of DNA’s four nucleotides, A, T, ... “When we activate this system (with an initiator DNA molecule), a DNA hairpin structure immobilized on the origami substrate ...

Cut the DNA and paste a new resistance gene very fast. On the other hand, if you have a protein-DNA complex that is rather weak and keeps falling apart, it has to be reassembled again and again.

Dec 21, 2022: Artificial DNA kills cancer (Nanowerk News) Researchers at the University of Tokyo have used artificial DNA to target and kill cancer cells in a completely new way.The method was ...

(BOSTON) -- Synthetic biologists and nanobiologists are re-purposing DNA, the hereditary material present in nearly all the body's cells, as a smart and stable self-assembling material to build ...

image: Oncolytic DNA hairpin pairs (oHPs) are introduced to the cancer cell. When the oHPs encounter the tumor-causing overexpressed microRNA (miRNA), they unravel to connect with the miRNA and ...