Perhaps our most defining characteristic as a species, the six-layered human cortex, hosts billions of neural connections that bestow Homo sapiens with higher-order thinking. But how does this ...

Scientists have created a super-map of the brain containing 30 million cells to trace the prenatal origins of diseases.

“It is an outstanding example of circuit analysis and a real experimental tour de force,” said neuroscientist Massimo Scanziani of the University of California, San Diego, who was not involved in the ...

Scientists have spent decades trying to understand whether the layered sheet of tissue that covers your brain follows one common pattern for handling information. Each region of the cortex contains ...

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...

Researchers at the UCL Queen Square Institute of Neurology find that the hippocampus sends signals to the visual cortex to predict what we are about to see. Our brains are powerful prediction machines ...

Researchers have discovered that mutations in the FOXJ3 gene act as a "master switch" failure, disrupting how the brain builds its layers and leading to FCD, a primary cause of drug-resistant epilepsy ...

REM (rapid eye movement) and non-REM (NREM) sleep stages contribute to systems memory consolidation in hippocampal-cortical circuits. However, the physiological mechanisms underlying REM memory ...

A new spatial transcriptomic approach captures the regulation of splicing and polyadenylation sites during pubescent brain development at near-single-cell resolution. An international collaboration, ...