The traditional approach was to use a bigger column, which provided a greater amount of stationary phase; and the second alternative was by displacement chromatography, which uses the stationary phase ...

Flash column chromatography differs from the older, slower version in that it uses pressurized gas to move the solvent through the column of the stationary phase.

Liquid chromatography uses a liquid mobile phase, with the stationary phase being on a planar surface or packed into a column. High-performance chromatography (HPLC) and ultra-high-performance liquid ...

How has the development of supercritical fluid chromatography (SFC) contributed to improved column technology? Supercritical fluid chromatography forced the development of more robust column ...

Gas chromatography (GC) has progressively evolved with the integration of ionic liquids and tailored stationary phases, offering enhanced separation efficiency, increased thermal stability, and ...

Ion-exchange chromatography (IEX) is a class of liquid chromatography used to separate organic and inorganic molecules, in particular biomolecules. In this article, we explore how the technique works ...

Choosing which chromatography column to install is perhaps the most impactful decision a chromatographer routinely makes. Since the separation of compounds by GC is governed by a molecule’s ...

High-performance liquid chromatography (HPLC) is a powerful tool for the enantioselective separation of chiral drugs. However, the selection of an appropriate chiral stationary phase (CSP) and ...

Chiral high performance liquid chromatography (HPLC) remains the most effective method for separating chiral molecules. HPLC involves running samples through a tube--known as a column--containing ...

Chiral high performance liquid chromatography (HPLC) remains the most effective method for separating chiral molecules. HPLC involves running samples through a tube -- known as a column ...

Lastly, resolution is affected by the stationary phase. The stationary phase, or the gel which lines the column, provides better resolution if it is more homogenous, and has smaller particle size.