In an open-label, two-period, two-sequence, cross-sectional, cluster-randomized, crossover trial, we assigned hospitals in Ontario, Canada, to use either lactated Ringer’s solution or normal saline ...

Successful clinical trial conduct balances participant safety, treatment efficacy and operational feasibility. But slow patient identification and enrollment, cost overruns and missed deadlines pose a ...

Correspondence to Dr Juliana S Oliveira, Sydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales 2050, Australia; juliana.oliveira{at}sydney.edu.au Intervention Intervention ...