Unlike normal cells, cancer cells contain amplified centrosomes and rely on centrosome clustering mechanisms to form a pseudobipolar spindle that circumvents potentially fatal spindle multipolarity ...

For almost a century, our understanding of the tiny structure at the centre of the cell called the centrosome was limited to its ability to organize mitotic spindles and other microtubule arrays.

A dividing cell duplicates its chromosomes and its centrosome, an organelle that helps divide the two sets of chromosomes equally to daughter cells, just once. Extra centrosome copies can lead to ...

Researchers provide insight into an old mystery in cell biology, and offer up new clues to understanding cancer. Scientists have unraveled the mystery of how cells count the number of centrosomes, the ...

Amilorides: Familiar antihypertensive medications with a novel potential against breast cancer. This is an ASCO Meeting Abstract from the 2014 ASCO Annual Meeting I. This abstract does not include a ...

Unseen and ongoing, thousands of times every second: to keep a complex organism like humans alive, an immense number of new cells must be continuously produced. Up close, each of these cell divisions ...

All life on earth depends upon the process of mitosis or cell division in which the chromosomal content of a cell is equally divided between two new cells. For mitosis to occur, the chromosomes in ...

In humans and other mammals, cardiac muscle cells stop replicating soon after birth, unlike the cardiac muscle cells in, say, zebrafish and amphibians. What do zebrafish and amphibian cardiomyocytes ...