CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Scientists have bred spiders that weave red draglines, proving that the animals’ silk can be genetically re-engineered.

A federal appeals court said the patent office made legal errors in awarding foundational patents for CRISPR-Cas9 to the ...

An appeals court has opened another chapter in the long-running CRISPR patent saga. | An appeals court has opened another ...

Adoptive cell therapy based on ex-vivo expanded tumor-infiltrating lymphocytes (TILs) has historically been most effective in ...

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 ...

In a new study published in Nature titled, “Custom CRISPR-Cas9 PAM variants via scalable engineering and machine learning,” researchers from Massachusetts General Hospital (MGH) and Harvard ...

Collaborating with CRISPR-Cas9 co-inventor Jennifer Doudna and Jill Banfield at ... Viral delivery of an RNA-guided genome editor for transgene-free germline editing in Arabidopsis, Nature Plants ...

Their results are published in Nature. "Our study is a first step in dramatically expanding our repertoire of effective and safe CRISPR-Cas9 enzymes. In our manuscript we demonstrate the utility ...

T he common house spider – you may look at it and think “Oh, what a beauty, my lovely house companion!” Or if you are not ...

Beam Therapeutics and Verve Therapeutics have each built their lead candidates on a technique billed as a safer alternative ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions—but there is always room for improvement. A new paper by investigators from Mass General Brigham ...