CRISPR-Cas9 genome editing articles from across Nature Portfolio. Atom; RSS Feed; Definition. CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner.

A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of ...

During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo. The cells ...

CRISPR Therapeutics’ CRSP first marketed product is the one-shot gene therapy Casgevy, approved in late 2023 and early 2024 ...

Bao noted a 2018 Nature Biotechnology paper indicated the presence of large deletions. ... due to CRISPR-Cas9 systems designed for treating sickle cell disease," he said.

Back in 1900 the life expectancy of people with Down Syndrome was 9 years. In 1984, it was 28 years, today it's leveled off ...

Researchers at the IPK Leibniz Institute have discovered a previously unknown protein that is central to plant reproduction.

In a new study published in Nature titled, “ Custom CRISPR-Cas9 PAM variants via scalable engineering and machine learning,” researchers from Massachusetts General Hospital (MGH) and Harvard ...

Their results are published in Nature. "Our study is a first step in dramatically expanding our repertoire of effective and safe CRISPR-Cas9 enzymes.

CRISPR RNA (crRNA) and Cas9: CRISPR DNA serves as a permanent record of past infections, but for bacteria to use these sequences to thwart viruses, they must convert them into DNA's cousin, RNA.

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases.But to date this ...

Gene therapy has always held enormous promise to correct genetic diseases, but turning that potential into treatments has been challenging.