For children who have uncontrolled asthma despite the use of low-dose inhaled corticosteroids (ICS), evidence to guide step-up therapy is lacking.We randomly assigned 182 children (6 to 17 years of ...

Study results, favoring long-acting β-agonists, are in tension with a recent FDA advisory. When asthma in children remains uncontrolled after monotherapy with inhaled corticosteroids (ICS), what ...

Lemanske, RF Jr, Mauger, DT, Sorkness, CA, et al. Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids. N Engl J Med 2010;362:975-985 Crossref ...

For patients with uncontrolled asthma despite the use of inhaled corticosteroids (ICS), common treatment options include addition of a long-acting beta agonist (LABA) and/or increasing the dose of ...

'Stepping up' asthma treatment ... "There may not be an ideal therapy for every patient, but these step-up treatments allow for improved ... 2022 — CHART categorizes children's risk of ...

Compared with tezepelumab, solrikitug demonstrated unique epitope binding and superior potency across several assays.

Most changes were step-up in doses during an asthma flare. Step-down changes were far less common. Asthma symptoms vary greatly among individuals and vary at times with each individual.

SAN DIEGO — Patients with asthma exacerbations despite inhaled corticosteroids and long-acting beta 2 agonists may benefit from stepping up treatment, according to a study presented at the ...

For children whose asthma is not well controlled and on low doses of inhaled corticosteroids, a long-acting beta-agonist (LABA) may be the most effective of three possible step-up treatments.

At the beginning of the study, the researchers' goal was for 25 percent of the 165 patients at all study sites to see a difference in their asthma symptoms while using at least one of the step-up ...

The Pediatric Asthma Yardstick, a new guideline from the American College of Allergy, Asthma and Immunology (ACAAI), offers a user-friendly 'operational document'. It helps health care ...

Interestingly, they did not step up the therapy after COVID-19. The thing that struck me the most was that Latino patients had longer durations of asthma exacerbations, but they did not have ...