There is currently no way to stop calcification of the aortic valve. If all else fails, the valve must be replaced. To better ...

Calcification process in aortic valves is responsible for blockages Northwestern Memorial leads search for first medical therapy for aortic valve disease Peer-Reviewed Publication ...

Heavy calcification reduces the accuracy of planimetry for valve area measurement (Figure 1), although transesophageal echocardiography images provide more reliable data. [ 12 ] (Enlarge Image) ...

(UPDATED) Lipoprotein(a) is associated with the development of aortic valve calcification (AVC), but the atherogenic lipoprotein does not appear to be linked to the progression of calcification over ...

The poor outcome of patients with symptomatic aortic stenosis has been well documented. 1–10 In view of the excellent results of aortic-valve replacement, 2,11–16 surgery is strongly ...

The most common cause of aortic stenosis in a person over age 70 years is calcification of a normal trileaflet aortic valve; this process is sometimes referred to as “senile degeneration.” ...

In the latest phase 2 trial involving 23 patients, ataciguat resulted in a 69.8% reduction in aortic valve calcification progression after six months, and patients on the drug also tended to ...

Valve size affects AVC levels: There was a significant association between the amount of calcification and the size of the aortic valve, regardless of sex. Misclassification risk: Individuals with ...

Aortic valve stenosis can happen due to calcium buildup (calcification) or scarring of the aortic valve. Aortic valve stenosis may occur in as many as 20% of older adults, according to the ...

Researchers have now proposed a molecular mechanism that links amyloid deposition in the aortic valve with degenerative calcification. They also theorize that other risk factors for CAVD, such as ...

Ataciguat, which slowed progression of native aortic valve calcification in the clinical trial, offers the potential for a once-in-a-lifetime procedure if they can reach the age of 65.