In the ED, adenosine is used to terminate supraventricular tachycardias (SVTs). It is also used by cardiologists for pharmacologic stress testing. Paroxysmal SVT has a prevalence of around 2.25 per ...

Adenosine is a short-acting endogenous molecule that is a purine nucleoside. The half-life is 6 seconds. Adenosine receptor activation results in multiple different actions depending on the location.

Naturally rewarding stimuli (i.e. food, sex, etc) increase the activity of dopamine cells in the mesocorticolimbic dopamine system causing increased dopamine release in brain areas such as the nucleus ...

Adenosine sensitive ventricular tachycardia occurs in structurally normal hearts and arises from the right ventricular outflow tract (pulmonary infundibulum). This gives it a left bundle branch block ...

ATP, ADP and other nucleotides can be released by stressed or apoptotic cells into the extracellular environment. They function as autocrine and paracrine signalling molecules by activating ...

The coffee paradox in adenosine-mediated antidepressant action. Depression (left) and coffee consumption (right) are both linked through adenosine signaling (center), creating a pharmacological ...