Suner said there are no real effective treatments for ace inhibitor-induced angioedema, but when they've used icatibant off-label on patients, he's seen dramatic improvement.

Researchers from Sweden aimed to compare characteristics between patients with ACE inhibitor-induced angioedema and cough by determining risk factors that differ between these adverse reactions.

Icatibant, a bradykinin B2 receptor antagonist, was no better than placebo in treating moderately severe angiotensin-converting enzyme inhibitor (ACEI) -induced angioedema of the upper airway ...

A bradykinin inhibitor brings a faster response for patients with ACE-inhibitor-induced angioedema in a small clinical trial.

Drug-induced skin swelling Bonn researchers identify novel risk locus in the genome for ACE inhibitor-induced angioedema Date: January 31, 2024 Source: Universitatsklinikum Bonn Summary ...

The authors note that most angioedema induced by inhibition of DPP IV occurs during concomitant angiotensin-converting enzyme inhibitor treatment and is likely to be mediated by bradykinin type 2 ...

In a triple blind, placebo-controlled phase-2 trial, researchers studied the drug Ecallantide for ACE inhibitor induced angioedema that failed to respond to the conventional therapy of ...

A multicenter clinical trial (NCT01919801) investigating icatibant for patients with ACE inhibitor-induced angioedema is expected to be completed next year, according to the drug manufacturer.

Angioedema is a rare but potentially life-threatening adverse reaction to ACE inhibitors. In a joint analysis of eight European study collectives, researchers from the University Hospital Bonn ...

Moellman says there's currently no treatment for ACE inhibitor induced (ACEI) angioedema, as the physiology of the condition is different—caused by the levels of the blood vessel-dilating ...