To achieve this, we created fluorescent-labeled dyneins in which a green ... in FRET within the HFG380B2 dynein. Figure 5: Model of the ATP hydrolysis cycle–dependent tail motions in the dynein ...

What Manfredi found new was the author’s next simulation of how motor neurons might “die back” from axon terminals, as is observed in animal models. Even when the ATP supply was down only at axon ...