Brock Purdy, Christian McCaffrey, Trent Williams, Nick Bosa, Fred Warner, George Kittle and Deommodore Lenoir should all be sitting out. A handful of potential starters may suit up to help solidify their status atop the depth chart, but that core group should strictly be focused on the regular season opener Sept. 7.

Late in the fourth quarter, wide receiver Luke Grimm muffed the punt, and it was recovered by the 49ers at the Chargers' 24-yard line. Two plays later, quarterback Carter Bradley and wide receiver Terique Owens connected for a 22-yard touchdown.