Each regional is a double-elimination format, with teams being seeded 1-4 at the local level. The 1 and 4 seed play in the first round of the regional, with the 2 and 3 matching up on the other side.

Clemson softball was announced as the No. 11 national seed in the NCAA Softball Tournament, which begins with the Clemson Regional on May 16.. The Tigers (44-12) will face USC Upstate (39-14) on ...