The Jacksonville Jaguars (4-12) are 4.5-point underdogs in a road AFC South matchup against the Indianapolis Colts (7-9) on Sunday, January 5, 2025 at Lucas Oil Stadium.NFL odds courtesy of BetMGM

Strangely, vibes are much better on the sidelines of the 4-12 team than the one at 7-9. While a loss is better for the Jaguars' chances at getting a top-five pick — even the first pick is still an outside shot — they are not playing with that mentality. Even if the Colts sneak out a victory here, it will not be by more than five points.

Mac Jones and the Jacksonville Jaguars (4-12) are in Indianapolis to face Joe Flacco and the Colts (7-9). This is a game with zero playoff implications but is one whose result carries massive draft ramifications especially for Jacksonville as nine teams are within one game of the first nine slots in the upcoming NFL Draft.

The Indianapolis Colts and Jacksonville Jaguars find themselves in similar predicaments Sunday. Neither will be playing again after Week 18.

With the Indianapolis Colts now officially out of playoff contention following last week’s “embarrassing” performance against the New York Giants, let’s take a look ahead to the 2025 NFL draft and where they are currently selecting.

NFL Week 18 odds, picks, predictions, TV channel, streaming information for Sunday football game between Jacksonville Jaguars and Indianapolis Colts.

The Indianapolis Colts and Jacksonville Jaguars opened this season with playoff hopes. Both had creative coaches, young quarterbacks, manageable schedules and what they anticipated were promising futures.