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The St. Louis Cardinals (48-42) and the Chicago Cubs (53-36) play the final game of their 3-game series Sunday night. First pitch from Wrigley Field is at 6:10 p.m. ET (ESPN). Let's analyze BetMGM Sportsbook's MLB odds around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Watch the St. Louis Cardinals vs. Chicago Cubs live stream from ESPN2 on Watch ESPN. First streamed on Monday, July 7, 2025.

The Cubs set a franchise record with eight home runs in an 11-3 rout of the Cardinals, including three from first baseman Michael Busch.

CHICAGO — Yohel Pozo pinch-hit a three-run homer to cap St. Louis’ five-run eight-inning rally, and the Cardinals came back to top the Chicago Cubs 8-6 on Saturday, ending a four-game slide. Pozo’s drive off Brad Keller reached Waveland Avenue to put St.

The Chicago Cubs set a franchise record by bashing eight home runs in a single game on their way to an Independence Day annihilation of the visiting St. Louis Cardinals, winning 11-3 on Friday.

New Orleans Saints running back Alvin Kamara 's first pitch ahead of Saturday's St. Louis Cardinals - Chicago Cubs game at Wrigley Field was so bad that he got a rare do-over. The five-time Pro Bowler sought immediate redemption after his botched first attempt landed on the edge of the infield grass and bounced into the left-handed batter's box.

Alvin Kamara proved why he’s a star running back—not a quarterback—after needing a redo on a wildly off-target first pitch ahead of the Chicago Cubs’ matchup against the St. Louis Cardinals at Wrigley Field on Saturday.